Why do mosquitoes bite you more than your friends? Science reveals the surprising skin chemistry behind it
ET Online May 25, 2025 01:22 AM
Synopsis

Wondering why mosquitoes always bite you more than your friends? A study reveals it's due to carboxylic acids your skin emits. These acids act like a magnet for Aedes aegypti, the mosquito that spreads dengue and Zika. Understanding this body chemistry could help develop personalized repellents, offering better protection against mosquito-borne diseases for millions worldwide.

Some people attract mosquitoes far more than others, and a 2022 study by Rockefeller University explains why. Individuals who emit higher levels of carboxylic acids through their skin are significantly more appealing to Aedes aegypti mosquitoes.
Ever wondered why, during a summer evening outdoors, you’re being relentlessly attacked by mosquitoes while your friends sip their drinks in peace? If you’ve blamed your blood type or bad luck, science has a more intriguing answer. A groundbreaking study has revealed that your body scent—specifically, the acids your skin emits—might be what’s turning you into a mosquito’s favourite meal.

A Scent Too Strong to Resist

In a 2022 study conducted by researchers at The Rockefeller University and published in the prestigious journal Cell, scientists uncovered that certain individuals produce significantly higher levels of carboxylic acids on their skin. These acids, a component of natural body odor, seem to act as a siren song to Aedes aegypti, the mosquito species infamous for spreading diseases like dengue, Zika, chikungunya, and yellow fever.

The research involved an unusual but telling experiment. Volunteers wore nylon stockings on their arms to collect their body scent. These were then cut into small pieces and placed in chambers with mosquitoes. What followed was a surprising and consistent pattern: the insects flocked to certain samples again and again, completely ignoring others.

Meet ‘Subject 33’: The Mosquito World’s Celebrity

One particular participant, known only as “Subject 33,” was an irresistible hit. “They won a hundred games,” said lead researcher Leslie Vosshall. “They were totally undefeated.” In every round, the mosquitoes were drawn to this subject’s scent more than anyone else’s. The secret? An unusually high presence of carboxylic acids on their skin.

This isn't just a fluke. These scent-based preferences remained stable over time, suggesting that mosquito attraction isn’t just about what you eat or what you wear—it’s rooted in your body chemistry.

Your Skin’s Chemical Climate Matters

Although the study doesn’t confirm why mosquitoes are obsessed with carboxylic acids, it strongly suggests that an individual’s unique “skin climate”—the natural cocktail of chemicals we exude—is what seals the deal for mosquitoes.

And while the researchers couldn't strip these acids from the high-attraction subjects to prove their exact role, they did note that human skin odor is a complex blend of many compounds. This study, however, focused exclusively on those with carboxylic acid groups, providing a promising lead in the quest to understand mosquito preferences.
Mosquito repellant
This scent-based preference, which remains consistent over time, could pave the way for more effective mosquito repellents and disease prevention.

The Bigger Picture: More Than Just Itchy Bites

This isn’t just about annoyance. Mosquitoes aren’t merely buzzing pests—they are deadly vectors that contribute to over 700 million infections globally each year. Understanding why some people are more prone to bites could change the game in mosquito control and repellent design.

Future repellents might target the specific chemical signatures mosquitoes crave, offering more personalized protection—especially crucial for vulnerable populations in disease-prone regions.

So, Why You?

If you’ve ever joked that you’re a “mosquito magnet,” it might be more scientific than you think. Your skin may be giving off signals that these insects find impossible to ignore. Until science finds a way to mask or neutralize those signals, your best defense might still be the classic combo of repellents, covered clothing, and clever timing.

But at least now, you can say: it's not you. It's your chemistry.

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