According to research, some persons with artificial hearts are able to repair heart muscle. This discovery might lead to new treatment options and perhaps even the cure for heart failure.
Heart failure does not yet have a cure. A transplant and a mechanical heart pump replacement are two options for treating severe heart failure. This may support the heart in pumping blood; it is called the left ventricular assist device.
Skeletal muscle “has a significant ability to regenerate after injury,” according to researchers from the University of Arizona’s College of Medicine in the United States.
The investigation was started by the team using tissue from individuals who had mechanical hearts. In order to determine if these samples included freshly created cells, they used their own novel technique of carbon dating human heart tissue, which involved researchers from Sweden and Germany.
People with these artificial hearts were able to renew muscle cells at a pace that was more than six times faster than that of healthy hearts, according to the findings, which were published in the journal Circulation.
Hesham Sadek, director of the varsity’s Sarver Heart Center in Tucson, said, “This is the strongest evidence we have, so far, that human heart muscle cells can actually regenerate, which is really exciting, because it solidifies the notion that there is an intrinsic capacity of the human heart to regenerate.”
Some patients with artificial hearts may be able to remove their devices due to a reversal of symptoms, the researcher added. This may occur in a person recuperating from a soccer injury if the mechanical heart gives their heart muscles the equivalent of bed rest.
According to Sadek, the results imply that it “may be possible to target the molecular pathways involved in cell division to enhance the heart’s ability to regenerate.”