Washington DC Washington DC: Researchers have created 3D video images of lung tissue developed in the laboratory, which have been created using a four-dimensional microscopy technique. What he has learned is nothing short of an unprecedented incident.
A new study shows that understanding flexibility – the ability to recover and revive the injured lung tissue – excessive time -born infants to pose a threat to life in infants to pose a threat to life, to further the treatment and prevention of lung disease. Can be important for.
Researchers at the Vanderbilt University and the University of Vendorbult Medical Center, using a four-dimensional microscopy technique, have created 3D video images of lung tissues developed in the laboratory.
“For the first time, we have been able to create its live image during the formation of the lungs, and can measure and measure cellular movements that come together to create an organ with sufficient surface area for gas exchange,” Jennifer The Associate Professor of Sukre, MD, Pediatric and Cell and Development Biology said.
The findings of the group, published as cover articles in JCI Insight, the journal JCI Insight of the American Society of Clinical Investigation, shows an important step towards better treatment and prevention of bronchoplamonary dysplasia (BPD), which two to four months ago About 50% of infants born.
“If we can understand how the lungs are made, we have a blueprint for how to develop new lungs after injury,” the first writer of the paper Nick Negrati, PhD said, who said, who is a senior post-doctor in a relaxed lab There are Fellows and who co-Nedd to research.
“Mice have an extraordinary ability to repair the lungs,” the paper's senior writer Sukre said, who directs the bio -model original Origins of Lung Disease (Bold) Center in VUMC. “I want to give children the superpower of rats.”
BPD premature children are required for oxygen and mechanical ventilation in the early days to help them breathe. Oxygen therapy is a two -edged sword as it can also harm delicate lung tissues.
