New York: A team of scientists has discovered the mechanism of abnormalities in immune cell activity, which Crohn's disease (Of one type Swollen intestinal disease – ibd) Can cause.

Crohn's disease one Chronic inflammatory condition Is, which Gastrointe Impresses In its symptoms Abdominal pain, diarrhea, weight loss, anemia and fatigue Can join.

Gamma delta t cells role

GI path white blood cellWhom Intraaphynellial lymphocytes (IELS) It is said, Gamma Delta T Cell Recepter (GAMMA DELTA IELS) Expresses These cells Protection from infection Provides and monitor the intestinal wall. But, Their number is found to be less in patients suffering from Crohn's disease।

Studies findings by Mount Sinai

Study led by Mount Sinai showed that Gamma delta is important for maintaining balance between IEL, Pro-inflammatory and controlling the immune system.But, Their functioning deteriorates during Crohn's diseaseBy which Longer Starts.

Mount Sinai's icon School of Medicine Associate professor of pathology in Karen Edelbalum Said, “In the previous studies, it was observed that the number of Gama Delta IEL among the people suffering from IBD. But it was not clear whether this deficiency was the cause of the disease or its effect.”

New biomarker in treatment of IBD

According to the study, Gamma delta IEL deficiency can be used as an forecasted biomarker to re -having disease or reaction to treatment।

In the future, Medical methods that increase the function of these immune cells can be developedWhich will benefit patients suffering from IBD and the development of this disease can be prevented in susceptible persons.

This research 'Science Immunology' Published in the magazine and can provide an important direction in the treatment of Crohn's disease.