The festive fixtures are finally here and all 20 of the Premier League's teams are set for action this week - although only two will lock horns on Boxing Day this year.
The majority of the next round of fixtures are set to take place on December 27, Manchester United and Newcastle will meet at Old Trafford on Boxing Day at 8pm before their rivals follow suit the following day, with all the big boys in action.
Here, Mirror Football rounds up all the latest injury news for all 20 Premier League teams as they get set to tackle the busy Christmas fixture schedule...
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AFC BournemouthBen Gannon-Doak, Tyler Adams, Veljko Milosavljevic are all set to be unavailable for the Cherries trip to Brentford on Saturday. Beyond those three, Andoni Iraola has reported no fresh injury concerns.
ArsenalThe Gunners will once again be without long-term absentee Gabriel. He could be joined on the sidelines by Piero Hincapie, who picked up an injury in the Carabao Cup triumph over Crystal Palace in midweek.
Cristian Mosquera, Ben White White, Kai Havertz and Max Dowman are also out.
Aston VillaEvann Guessand has linked up with the Ivory Coast for the Africa Cup of Nations. Ross Barkley, Tyrone Mings and Pau Torres are also out, while Harvey Elliott is also a doubt.
BrentfordKeith Andrews will be without Frank Onyeka and Dango Outtara, who are at the Africa Cup of Nations. Josh Dasilva, Fabio Carvalho and Antoni Milambo are Brentford's other absentees.
BrightonCarlos Baleba is one of four players expected to miss their game at Arsenal. Stefanos Tzimas, Adam Webster and Solly March will also be unavailable this weekend.
BurnleyAxel Tuanzebe and Lyle Foster are both at the Africa Cup of Nations but other Clarets stars are also set to miss out against Everton. Connor Roberts, Jordan Beyer, Zeki Amdouni are injured while Hannibal Mejbri is banned, but Maxime Esteve is back in contention.
ChelseaRuben Colwill, Romeo Lavia and Dario Essugo are unavailable for Chelsea's game with Aston Villa. Willian Estevao could return, though, after sitting out the Blues' last two matches, while Liam Delap may also feature.
Crystal PalaceIsmaila Sarr misses out due to the Africa Cup of Nations. Daichi Kamada, Cheick Doucoure and Daniel Munoz all remain injured and will play no part on Sunday when Palace play Tottenham.
EvertonDavid Moyes will have to make do without Iliman Ndiaye and Idrissa Gueye (Africa Cup of Nations) against Burnley. Jarrad Branthwaite and Seamus Coleman are both sidelined with hamstring injuries and will also miss out.
FulhamHarry Wilson could be a doubt after limping off in the win over Nottingham Forest on Monday. Rodrigo Muniz and Ryan Sessegnon are still absent while Calvin Bassey, Samuel Chukwueze and Alex Iwobi are all at the Africa Cup of Nations with Nigeria.
LeedsLukas Nmecha could return for Leeds but their Sunday game vs Sunderland will come too soon for Sean Longstaff and Daniel James.
LiverpoolAlexander Isak is the big Liverpool absentee after undergoing surgery on a leg fracture earlier this week. Joe Gomez and Wataru Endo have both been ruled out while Mohamad Salah is at the Africa Cup of Nations.
Dominik Szoboszlai misses out through suspension after accumulating five yellow cards but Cody Gakpo and Conor Bradley are '50-50' and could play some part.
Manchester CityMateo Kovacic is out for Manchester City while Jeremy Doku, Oscar Bobb, Rodri and John Stones are all doubts. Rayan Ait-Nouri and Omar Marmoush are at the Africa Cup of Nations.
Manchester UnitedBruno Fernandes and Kobbie Mainoo are likely to miss out with the former definitely sidelined. Harry Maguire and Matthijs de Ligt are doubts.
NewcastleSven Botman, Kieran Trippier, Emil Krafth, Dan Burn and Tino Livramento are all ruled out for Newcastle but Nick Pope could be fit enough to return to the squad.
Nottingham ForestOla Aina, Ibrahim Sangare, Willy Boly, Chris Wood and Ryan Yates will play no part in Saturday's home game against Manchester City.
SunderlandLuke O'Nien is still suspended for the Black Cats, who have SIX players at the Africa Cup of Nations: Arthur Masuaku, Habib Diarra, Noah Sadiki, Reinildo, Chemsdine Talbi and Bertrand Traore.
TottenhamCristian Romero and Xavi Simons are both suspended after being sent off in the defeat against Liverpool. Yves Bissouma and Papa Mate Sarr are both at the Africa Cup of Nations.
West HamAaron Wan-Bissaka and El Hadji Malick Diouf are the Hammers' only two absentees with both players at the Africa Cup of Nations.
WolvesYerson Mosquera is back but Wolves will be without captain Toti Gomes for their game with Liverpool due to a hamstring issue.
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