of the blood, such as leukemia, lymphoma, and multiple myeloma of cancer It is a very stressful time for diagnosed patients. Treatment is often very difficult and there is a constant fear of relapse. However, this picture is changing now due to ‘Precision Onco-Hematology’. In this method, ‘special treatment’ is prescribed according to the nature of each patient’s disease, which gives the patient a new hope for a long and healthy life.
By identifying the exact type of cancer in a patient’s body, doctors can now design treatments that are more effective and have fewer side effects. This not only saves the patient’s life, but also helps to make their life more bearable during the treatment. Dr. Amrit Kaur Kaler, Consultant, Molecular Pathology, Kokilaben Dhirubhai Ambani Hospitals Mumbai has given more information.
How is the treatment?
One of the greatest examples of the success of this treatment is Chronic Myeloid Leukemia (CML). Scientists discovered the genetic defect ‘BCR-ABL1’ that causes this disease. This discovery led to the development of drugs like ‘Tyrosine Kinase Inhibitors’, which directly attack the root of cancer. Earlier this disease was considered to be very life threatening but now due to proper medicine patients can live a normal life with this disease. They can do their work, study and be happy with family. Proper treatment can greatly improve quality of life.
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Altered appearance
Very serious blood malignancies such as acute myeloid leukemia (AML). on cancer The nature of treatment has also changed. Scientists have identified genetic defects such as FLT3, IDH1/2 and NPM1 that cause the disease. This discovery has made it possible to create special drugs that directly target the root cause of the disease. Such personalized treatment results in better drug benefit for patients, longer disease control and increased patient survival. This proves that personalized treatment can be very effective even in aggressive cancers.
What exactly do drugs do?
Similarly, ‘JAK2’ drugs have become the mainstay of treatment in the blood disease MPN (Myeloproliferative Neoplasm). Many patients have a genetic defect called ‘JAK2’, which causes an uncontrolled increase in the number of blood cells in the body. This puts the patient at risk of constant fatigue, enlarged spleen and blood clots. Newer drugs work directly on this defect, reducing the symptoms of the disease and preventing the disease from progressing. With such treatments tailored to each patient’s disease type, even chronic diseases can now be better managed.
Modern inspection
In the wake of global advancements, Kokilaben Dhirubhai Ambani Hospital has now introduced a state-of-the-art test called ‘Myeloid Research Assay’. It is an advanced ‘Next-Generation Sequencing – NGS’ test, which simultaneously detects all the important genetic defects associated with blood cancer.
40 key genes and 29 fusion panels are tested in this single test. These include major blood cancers such as acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), myeloproliferative neoplasm (MPN), CML, chronic myelomonocytic leukemia (CML), and juvenile myelomonocytic leukemia (JML). As this test is available in the hospital itself, patients get a quick and accurate diagnosis of the disease. This reduces confusion and allows the patient to start the right treatment at the right time for their disease, increasing their chances of improvement.
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Solutions tailored to patient needs
According to experts, the combination of accurate diagnosis and modern medicine means not only treating cancer, but curing the patient as a whole. When the treatment is adapted to the needs of the patient, the positive difference is also felt by the family: there are no frequent visits to the hospital, the treatment is more effective and the patient can lead a normal life sooner. For many patients, this progress provides a more tolerable daily life, new hope for the future, and increased confidence that the disease will not recur.
Kokilaben Hospital has once again proved its commitment to patient care by launching ‘Myeloid Research Assay’. With this initiative, world-class ‘Precision Oncology’ is now easily accessible to patients in India. This breakthrough is not only a medical breakthrough for patients facing blood cancer and their families, but also a new hope for the future, relief and assurance of a happy cancer-free life.
