Jerusalem Jerusalem: A new international study has first identified the unique sub-glory of fat cells. According to the report of the Seenhua News Agency, researchers at the Ben Gurian University (BGU) of Israel mentioned that this study is individual medicine in obesity Can pave the way
This study conducted as part of the International Human Cell Atlas project maps the fat cell populations in various human fat tissues, focusing on the subcutaneous and the intestinal fat. Using, the team attached unique “barcodes” from individual cells to RNA, allowing them to identify different cell types within fat tissue.
Research published in Nature Genetics magazine revealed pre-unknown sub-types, including fat cells involved in regulating inflammation, blood vessel construction, external protein deposition, and fibrosis. In addition, one of the unique types of fat cells identified for the first time in this research appeared only in the tissues inside the abdomen. In the last 30 years, the understanding of fat tissue was developed only from an energy storage site and for the production of protein. It is known that controls appetite, eating and energy expenditure, such as leptin, which affects brain control centers.
While most of the fat cells were the same in the subcutaneous and intestinal fat, subtle differences were found in their narrative communication. The intestinal fat cells were more busy with pro-inflammatory processes interacting with immune cells, while subcutaneous fat cells focused on anti-inflammatory processes.
The team also found that the prevalence of these unique fat cells was to the metabolic complications of obesity, the more severe insulin resistance in the tissue is as much as their relative ratio. According to the researchers, if unique fat cells predict individual risk to obesity complications or treatment response, the conclusions can significantly carry forward the remedies for individual obesity.